Endocrine Abstracts

The problem of the influence of disturbances of Hyper- or Hyponatraemia is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. Electrolyte disbalance affected on the formation of mental disorders, their structure and dynamics in the literature has not been sufficiently studied. Perhaps there are certain factors and patterns of the influence of hypo- and hypernatraemia on mental activity with various lesions of the brain, which requi...

Introduction: The risk of pituitary apoplexy (PApopl) is up to 9.5%. In 80% of cases, it is the first manifestation of the disease.Material and methods: The study included 94 PApopl from 1 day up to 9 years. Conservative treatment was performed in 37 cases, and 59 were operated on including 14 giant posthemorrhagic cysts. The probability of resorption – it is possible in 85%, instead of cysts (the probability of resorption of ~ 15%). After 3 months,...

Objective: Prospective study of cabergoline effect in newly diagnosed patients with giant invasive prolactinomas.Patients and methods: The study group included 121 patients with giant prolactinomas (tumors larger than 40 mm in size); among them 49 patients had tumors larger than 60 mm in size. 91 male and 30 female aged 16–67 years (median 37) were treated with 0.5–3.5 mg/week (mean 1.5 mg) cabergoline. The treatment period was 6–120 month...

Among tumors of the diencephalic region there are: pituitary adenomas, craniopharyngiomas, gliomas, meningiomas and others. They differ in location, histology, clinic with corresponding hormonal disorders. Emotional disorders in the clinic of tumors of the diencephalic region are revealed in 2–67% by the literature. Emotional disturbances with hormone-active pituitary adenomas there are 30–60%, and with non-functioning pituitary adenomas there are ones less than 6%. ...

Objective: To study the clinical, diagnostic and morphological characteristics and treatment outcomes of TSH-secreting pituitary tumors.Patients and methods: The study included 21 patients with pituitary adenoma and a normal or elevated TSH level and elevated fT4 and fT3 levels who were operated on at the Neurosurgical Institute in the period between 2002 and 2015. Before surgery, in the early postoperative period, and 6 months afte...

Introduction: Craniopharyngiomas (CF)- benign epithelial tumors that develop from the remnants of Rathke’s pouch cells. Most often, CF manifest themselves in two age groups: in children 5–14 years old making 5.6–13% of intracranial tumors and in adults 50–74 years old making 2–5%.Materials and methods: In the last decade, the Institute annually for the surgical treatment received 100–120 patients with CF. The total number of...